Motif ID: FOX{I1,J2}.p2

Z-value: 1.094


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ2chr12_+_80765080.204.6e-01Click!
FOXI1chr5_+_1694654780.194.9e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_30238961 1.832 NM_033229
TRIM15
tripartite motif containing 15
chr5_+_140200995 1.461 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr7_+_6583560 1.356 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr19_-_14646626 1.208 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr3_-_15357878 1.208 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chrX_+_134803450 1.141 NM_018666
SAGE1
sarcoma antigen 1
chr4_+_167013859 1.121 NM_012464
TLL1
tolloid-like 1
chr22_-_41366550 1.052 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr6_+_150304813 1.037 NM_025217
ULBP2
UL16 binding protein 2
chr8_+_27687821 1.019 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr4_+_71806538 0.977 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr20_+_19818209 0.967 NM_018993
RIN2
Ras and Rab interactor 2
chr11_+_69176391 0.935 CCND1
cyclin D1
chr3_+_46423682 0.876 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr15_-_53587723 0.873 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr4_-_70861301 0.873 NM_001891
CSN2
casein beta
chr1_+_149877955 0.835 SNX27
sorting nexin family member 27
chr12_-_21649019 0.833 NM_021957
GYS2
glycogen synthase 2 (liver)
chr2_+_161725172 0.831 TANK
TRAF family member-associated NFKB activator
chr6_+_26473376 0.826 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr12_-_7487989 0.757 NM_174941
CD163L1
CD163 molecule-like 1
chr16_+_29971971 0.738 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr15_+_40484249 0.732 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr1_+_148747110 0.730 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr17_+_53587492 0.729 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr1_+_36520751 0.712 THRAP3
thyroid hormone receptor associated protein 3
chr10_+_97461525 0.708 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr11_-_102250876 0.659 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr5_+_147775652 0.644 FBXO38
F-box protein 38
chr13_+_51496679 0.642 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr8_-_15140162 0.635 NM_139167
SGCZ
sarcoglycan, zeta
chr4_+_72321113 0.633 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr22_+_21384862 0.632 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr8_+_7742811 0.619 NM_058203
NM_001081552
SPAG11B
SPAG11A
sperm associated antigen 11B
sperm associated antigen 11A
chr5_-_96175560 0.610 NM_001198541
ERAP1
endoplasmic reticulum aminopeptidase 1
chr12_+_21175394 0.606 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr19_-_5797465 0.605 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr22_+_20350272 0.602 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr16_+_65558878 0.589 NM_001185176
CES3
carboxylesterase 3
chr15_+_56217686 0.588 NM_020980
AQP9
aquaporin 9
chr3_+_42825957 0.584 NM_001296
CCBP2
chemokine binding protein 2
chr2_+_38009405 0.583 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr9_-_115877104 0.573 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_134042500 0.569 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr16_+_8622974 0.565 NM_024109
METTL22
methyltransferase like 22
chr12_-_51065629 0.557 NM_033045
KRT84
keratin 84
chr4_+_86968069 0.547 ARHGAP24
Rho GTPase activating protein 24
chr5_-_156705250 0.543 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr3_-_194579207 0.540 NM_198505
ATP13A5
ATPase type 13A5
chr22_+_40372957 0.538 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr1_-_21249974 0.537 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_-_23955223 0.536 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr2_+_151922350 0.531 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_42934910 0.530 YBX1
Y box binding protein 1
chr10_+_111957292 0.523 NM_130439
MXI1
MAX interactor 1
chr19_-_42393225 0.516 NM_152279
ZNF585B
zinc finger protein 585B
chr10_-_48426868 0.508 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr4_-_68432293 0.503 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr10_-_50012058 0.494 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr5_+_159368690 0.490 TTC1
tetratricopeptide repeat domain 1
chr16_+_29971955 0.486 ALDOA
aldolase A, fructose-bisphosphate
chr13_-_35327798 0.480 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr7_+_75928907 0.476 NM_001102594
NM_001102595
NM_020892
DTX2


deltex homolog 2 (Drosophila)


chr10_-_46039941 0.468 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr2_+_3620296 0.465 NM_024027
NM_199235
COLEC11

collectin sub-family member 11

chr8_+_67751007 0.464 NM_019607
C8orf44
chromosome 8 open reading frame 44
chr16_-_4757125 0.462 NM_021646
ZNF500
zinc finger protein 500
chrX_-_101613387 0.458 NM_017809
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr2_-_135498716 0.455 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr9_-_139047112 0.455 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr4_-_77097582 0.453 SDAD1
SDA1 domain containing 1
chr16_+_80370400 0.453 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_155788775 0.452 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr5_+_175241449 0.448 CPLX2
complexin 2
chr12_-_101115677 0.446 NM_002674
PMCH
pro-melanin-concentrating hormone
chr7_+_111908143 0.442 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr15_+_22778233 0.441 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr6_+_30722794 0.441 NM_001109938
NM_001161376
NM_145029
C6orf136


chromosome 6 open reading frame 136


chr4_-_186693574 0.440 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr19_+_49221333 0.440 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr16_+_6763810 0.437 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_+_30161173 0.435 TM9SF4
transmembrane 9 superfamily protein member 4
chr17_-_39500512 0.430 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr13_+_96592051 0.426 MBNL2
muscleblind-like 2 (Drosophila)
chr12_+_53699995 0.425 NM_021191
NEUROD4
neurogenic differentiation 4
chr17_+_31112028 0.421 NM_145272
C17orf50
chromosome 17 open reading frame 50
chr1_+_169421011 0.419 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr4_+_186587537 0.419 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr5_+_140546839 0.413 NM_019119
PCDHB9
protocadherin beta 9
chr22_-_35428848 0.410 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr12_+_54672766 0.410 RAB5B
RAB5B, member RAS oncogene family
chr7_+_89712423 0.410 NM_001039706
NM_001160138
C7orf63

chromosome 7 open reading frame 63

chr6_+_45404031 0.403 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr2_+_241193492 0.400 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr1_+_151240846 0.398 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr5_+_140454382 0.398 NM_018936
PCDHB2
protocadherin beta 2
chr3_+_87359088 0.397 NM_014043
CHMP2B
chromatin modifying protein 2B
chr9_-_129381086 0.397 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr2_+_158666627 0.396 NM_173355
UPP2
uridine phosphorylase 2
chr3_-_188492163 0.393 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr10_+_18589589 0.388 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr10_-_74384485 0.387 NM_032562
PLA2G12B
phospholipase A2, group XIIB
chr2_-_218739891 0.385 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr20_+_10147455 0.382 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr15_-_41728329 0.381 NM_054020
NM_172095
NM_172097
CATSPER2


cation channel, sperm associated 2


chr3_-_140677990 0.381 NM_004164
RBP2
retinol binding protein 2, cellular
chr7_-_122130201 0.371 NM_198085
RNF148
ring finger protein 148
chr1_-_171441234 0.371 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr2_+_95621492 0.370 NM_138800
TRIM43
tripartite motif containing 43
chr19_-_4351470 0.370 NM_003025
SH3GL1
SH3-domain GRB2-like 1
chrX_+_15428820 0.367 NM_203281
BMX
BMX non-receptor tyrosine kinase
chrX_+_101356905 0.367 NM_017809
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr19_-_44497815 0.367 NM_020862
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr18_-_59480082 0.366 NM_006919
SERPINB3
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 3
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chrX_-_50403412 0.364 SHROOM4
shroom family member 4
chr4_-_186814852 0.364 SORBS2
sorbin and SH3 domain containing 2
chr11_-_62668268 0.364 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr12_-_51332214 0.362 NM_000423
KRT2
keratin 2
chr1_-_150398327 0.362 NM_001122965
RPTN
repetin
chr20_-_29751755 0.361


chr3_+_173043832 0.357 NM_001164436
TMEM212
transmembrane protein 212
chr9_+_102380156 0.353 NM_001018116
MURC
muscle-related coiled-coil protein
chr21_+_39745649 0.353 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr5_+_140698537 0.353 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chrX_+_154880439 0.352 NM_002186
IL9R
interleukin 9 receptor
chr5_-_137876416 0.351 ETF1
eukaryotic translation termination factor 1
chr2_-_77602843 0.350 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr11_-_30910074 0.348 NM_020869
DCDC5
doublecortin domain containing 5
chr4_+_120029426 0.343 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr11_+_55351270 0.343 NM_001004739
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr19_+_56671649 0.343 NM_001080405
CEACAM18
carcinoembryonic antigen-related cell adhesion molecule 18
chr11_-_17147863 0.343 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr7_-_84589182 0.343 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr1_+_82038669 0.342 NM_012302
LPHN2
latrophilin 2
chr1_+_24713396 0.341 RCAN3
RCAN family member 3
chr5_+_128468785 0.341 ISOC1
isochorismatase domain containing 1
chr20_+_30160952 0.339 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr1_+_195503956 0.337 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr1_+_20081424 0.336 NM_015207
OTUD3
OTU domain containing 3
chr1_+_203179976 0.335 NM_001160331
NFASC
neurofascin
chr17_+_55098280 0.335 CLTC
clathrin, heavy chain (Hc)
chr7_-_13997574 0.335 NM_001163148
ETV1
ets variant 1
chr19_+_46951237 0.334 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr4_-_70115037 0.334 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr9_-_139262009 0.333 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr1_+_51340487 0.333 NM_001136508
C1orf185
chromosome 1 open reading frame 185
chr12_+_130004404 0.329 NM_198827
GPR133
G protein-coupled receptor 133
chr20_+_43423990 0.327 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr16_+_68938264 0.326 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr19_-_59258846 0.325 NM_198481
VSTM1
V-set and transmembrane domain containing 1
chr1_-_94359266 0.325 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr15_+_70477707 0.324 NM_001080462
TMEM202
transmembrane protein 202
chr11_-_59707074 0.322 NM_022349
NM_152851
NM_152852
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr6_+_108988797 0.321 FOXO3
forkhead box O3
chr11_+_48194937 0.321 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr19_-_58486686 0.320 NM_033341
BIRC8
baculoviral IAP repeat containing 8
chr1_+_20081510 0.320


chr5_+_159368721 0.320 TTC1
tetratricopeptide repeat domain 1
chr11_+_65024889 0.320 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr7_+_156677777 0.319


chr2_+_166137091 0.319 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr1_-_110735158 0.318 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr5_-_172016174 0.317


chr5_+_159368733 0.316 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr12_-_46786107 0.315 SENP1
SUMO1/sentrin specific peptidase 1
chr21_-_14840506 0.314 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_131333173 0.314 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_+_20081495 0.313 OTUD3
OTU domain containing 3
chr9_+_76302071 0.313 NM_006914
RORB
RAR-related orphan receptor B
chr1_+_182287388 0.311 NM_001127394
NM_052965
TSEN15

tRNA splicing endonuclease 15 homolog (S. cerevisiae)

chr11_+_64950402 0.311


chr9_+_124321239 0.310 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr8_+_7656261 0.309 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr2_+_183290912 0.309 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chrX_+_22927998 0.309 NM_182699
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
chr4_+_8935987 0.309 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr9_-_98815676 0.305 HIATL2
hippocampus abundant transcript-like 2
chr10_+_71232281 0.303 COL13A1
collagen, type XIII, alpha 1
chr1_+_157676135 0.303 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr4_-_64957595 0.302 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_5212168 0.301 NM_000519
HBD
hemoglobin, delta
chr6_+_46822657 0.300 NM_001162435
LOC100287718
ankyrin repeat domain containing gene
chr8_+_50987149 0.296 NM_018967
SNTG1
syntrophin, gamma 1
chr12_-_55614311 0.294 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr12_+_34066482 0.293 NM_032834
ALG10
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)
chr4_+_8964460 0.293 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr16_+_3345889 0.293 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr14_-_80475636 0.291 NM_152446
C14orf145
chromosome 14 open reading frame 145
chr21_-_30577120 0.291 NM_001085455
KRTAP24-1
keratin associated protein 24-1
chr7_+_136203938 0.287 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr8_-_7427584 0.286 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr3_+_152970904 0.285 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr18_-_46046771 0.284 NM_145020
CCDC11
coiled-coil domain containing 11
chr13_+_109932934 0.284 COL4A2
collagen, type IV, alpha 2
chr19_+_56958452 0.284 NM_001462
FPR2
formyl peptide receptor 2
chr12_+_38306238 0.284 NM_001031748
C12orf40
chromosome 12 open reading frame 40
chr15_-_64436045 0.283 NM_017858
TIPIN
TIMELESS interacting protein
chr17_-_64823368 0.283 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr21_-_31041390 0.283 NM_181617
KRTAP21-2
keratin associated protein 21-2
chr17_-_44006808 0.283 NM_002146
HOXB3
homeobox B3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.92 6.18e-06 GO:0007608 sensory perception of smell
1.86 7.52e-06 GO:0007606 sensory perception of chemical stimulus
1.17 3.90e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 3.87e-03 GO:0071944 cell periphery
1.18 4.15e-03 GO:0005886 plasma membrane
1.23 4.07e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.96 7.14e-07 GO:0004984 olfactory receptor activity
1.46 4.07e-03 GO:0004930 G-protein coupled receptor activity